Fatal torsade de pointes following jaundice in a patient treated with disopyramide.
نویسندگان
چکیده
A case of fatal torsade de pointes in a 53 year old patient treated with disopyramide is described. The arrhythmia followed the development of acute hepatocellular dysfunction and may have been due to failure of the liver to efficiently degrade the drug to its metabolites.
منابع مشابه
Torsade de pointes induced by N-acetylprocainamide.
N-Acetylprocainamide (NAPA), a class III antiarrhythmic drug, caused torsade de pointes in a 72 year old woman who had this arrhythmia on two previous occasions while being treated with quinidine and disopyramide. Initial evaluation with an intravenous infusion of NAPA indicated a favorable antiarrhythmic response. The QTC interval was prolonged, but the 2.4 ms/microgram per ml incremental QTC ...
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ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 65 763 شماره
صفحات -
تاریخ انتشار 1989